Expression of Connexin 32 and Connexin 43 gap junction proteins in basal and squamous cell carcinomas

Gap junctions play a role in intercellular communication the epithelium, muscle and nerve tissues, many more tissues organs. These linking regions proteins forming them are called connexins (Cx). Recent studies show that cellular homeostatic equilibrium can be influenced by connexins. In this study, expression of Cx43 Cx32 basal cell carcinoma (BCC) squamous carcinomas (SCC) is tried studied. A total 45 cases, 23 male 22 female, were included study. Twenty cases SCC twenty-five BCC. Retrospective data from records examined specimens investigated immunohistochemistry staining. It was determined results Cx 43 32 staining changed according to tumor type (P = 0,020). did not change sex age, BCC subtype, location. Losses have been shown associated with types. We believe it used as support marker differential diagnosis.